Wilkinson opened in 1998 on Bethnal Green’s Cambridge Heath Road in the heart of the East End of London. Anthony Wilkinson started in the mid 90s curating shows in temporary spaces and alternative venues and also ran a project space in central London. In 2000 he joined with co-director Amanda Wilkinson. Since 1998 the gallery has grown to represent many international artists and has developed the careers of less established artists to international status.